Inserm U1096 EnVI
Research performed in Inserm U1096 Unit in Rouen, concerns evaluation of the mechanisms behind and novel treatments of cardiovascular diseases, focusing on vascular protection, treatment of aortic stenosis, and improvement of cardiac contractile function. This research is transversal, and performed both in experimental models and in human.
Our work mostly concerns the protection of vascular endothelial cells in the context of cardiovascular risk factors or cardiovascular diseases (hypertension, diabetes, myocardial infarction, heart failure etc. ).
Our work concerns the search for new preventive treatments of aortic stenosis, and improvement of current treatments focusing especially on transcutaneous aortic valve implantation (TAVI) , within the frame of the RHU STOP-AS .
Development and assessment of new treatments of diastolic dysfonction, chronic heart failure and acute cardiac decompensation, via pharmacological approaches or novel biotherapies for stimulation of cardiac angiogenesis and lymphangiogenesis.