Major Contributions

Endothelium

  • Role of cytochrome P450-derived hyperpolarizing factors (EDHF) in endothelium-dependent vasodilatation in human, and consequences of its pharmacological restoration in cardio-metabolic diseases (PMID: 20083732 22412088 26022136)
  • Endothelial protective effects and reduction of heart failure by tyrosine phosphatase 1B inhibition (PMID: 22446161 17101854 24760754 27059805 29569957)
  • Dopamine and endothelial dysfunction in autosomal dominant polycystic kidney disease (PMID: 25029430)
  • Endothelial impact of antiphosphospholipid syndrome and thrombotic thrombocytopenic purpura (PMID: 25047402 27501520)

Valvulopathy

Heart Failure

  • Beneficial effects of pharmacological heart rate reduction in heart failure (PMID:14981003 22075752)
  • Aldosterone signaling in heart failure (PMID: 26902493 29061727)
  • Treatment of heart failure by localized slow delivery of angiogenic or lymphangiogenic growth factors (PMID:21824923 26933083)
  • Role of cardiac lymphatics and therapeutic lymphangiogenesis in myocardial infarction and heart failure (PMID: 26933083)

 

INSERM U1096

Endothelium, Valvulopathy
& Heart Failure

RĂ©alisation Internet Bordeaux.

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