Major Contributions

Endothelium

Role of cytochrome P450-derived hyperpolarizing factors (EDHF) in endothelium-dependent vasodilatation in human, and consequences of its pharmacological restoration in cardio-metabolic diseases (PMID: 20083732 22412088 26022136 30885203 31436984)
Endothelial protective effects and reduction of heart failure by tyrosine phosphatase 1B inhibition (PMID: 22446161 17101854 24760754 27059805 29569957)
Dopamine and endothelial dysfunction in autosomal dominant polycystic kidney disease (PMID: 25029430 30607032)
Endothelial impact of antiphosphospholipid syndrome and thrombotic thrombocytopenic purpura (PMID: 25047402 27501520 30870459)

Discovery and clinical evaluation of percutaneous aortic valve replacement (PMID:12473543 15226213 22551129 26369474 30028301)

Beneficial effects of pharmacological heart rate reduction in heart failure (PMID:14981003 22075752) and acute heart failure (PMID: 33471946)

Aldosterone signaling in heart failure (PMID: 26902493 29061727 29862614 29981797 29862614)

Treatment of heart failure by localized slow delivery of angiogenic or lymphangiogenic growth factors (PMID:21824923 26933083 30333526 )

Role of cardiac lymphatics and therapeutic lymphangiogenesis in myocardial infarction and heart failure (PMID: 26933083 30333526 32762908 32404007 32451732 35689481)

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